Anti-body Coupled T Receptor Therapy Market is Predicted to See Lucrative Gains Over forecast period
Anti-body coupled T receptor (ACTR) therapy is a sort of cancer immunotherapy in which the body's own immune system is used to kill malignant cells. Antibody-linked T receptor therapy takes T cells from the patient's body, modifies them to express a specific T cell receptor, multiplies them in the lab, and then administers them along with antibodies that target them. The main benefit of this treatment is that T lymphocytes do not assault typical antigens in the bloodstream. They do, however, assault antigens found on malignant cells. This method is feasible because tumor-specific monoclonal antibodies are delivered in conjunction with ACTR T cells. Furthermore, when compared to other cancer therapies, it is a cost-effective treatment.
The global anti-body coupled T receptor therapy market is predicted to develop due to
the rising incidence of cancer around the world. Cancer is one of the most
common non-communicable diseases and the second largest cause of death
worldwide, according to the World Health Organization (WHO). According to the
International Agency for Research on Cancer (IARC), there were approximately
14.1 million new cases, 8.8 million deaths, and 32.6 million cancer patients
worldwide in 2012. Furthermore, according to a 2017 estimate by the Leukemia
and Lymphoma Society, the United States alone is predicted to see an annual
prevalence of 816,834 and 80,500 new cases of lymphoma in 2017. As a result,
the worldwide anti-body coupled T receptor therapy market would be propelled by
such a large number of cancer patients.
Furthermore,
ACTR therapy differs from other adoptive T cell transfer technologies, such as
CAR-T cell therapy, in its methodology. Side effects of CAR-T therapies like
Kymriah (Novartis AG) and Yescarta (Gilead Lifescience, Inc.) include cytokine
release syndrome and neurological damage. This is projected to promote ACTR
therapy usage and, as a result, move the global anti-body coupled T receptor
therapy market forward shortly. CAR-T therapy can also be used to
treat common diseases such as non-Hodgkin lymphoma, acute lymphoblastic leukemia,
and multiple myeloma. Solid tumor cancers such as neuroblastoma and breast
cancer are also treated with ACTR treatment.
The high
cost of a product might be a big stumbling block to the market's expansion.
Kymriah, a CAR-T treatment, for example, costs roughly US$ 475,000 per patient.
Given the high cost of CAR-T therapy, it is reasonable to predict that
anti-body coupled T receptor therapy will cost similarly because it operates in
the same section of Immuno oncology, which will limit the worldwide anti-body
coupled T receptor therapy market's growth.
To
achieve a competitive advantage in the market, leading organizations are focusing
on various techniques such as collaboration and agreement. Unum Therapeutics is
the sole company working on anti-body linked T receptor treatment at the
moment. It has several products under development, which differ depending
on the technology utilized to produce receptors in patients' T cells, such as
mRNA.

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