The Global Secondary Hyperparathyroidism Treatment Market is expected to reaching USD 7282.20 million by 2025
Secondary hyperparathyroidism is a disease of the parathyroid glands that causes an increase in the production of parathyroid hormone (PTH) to maintain normal calcium levels in the blood. The disease is caused by an underlying chronic kidney disease in which the kidneys do not clean the phosphorus in the blood. The excess phosphorus in the blood causes a drop in calcium levels, resulting in secondary hyperparathyroidism. PTH levels are high in the early stages of secondary hyperparathyroidism, but calcium levels are low or normal. High PTH levels cause cardiovascular complications, low blood count, abnormal fat and sugar metabolism, bone weakness, and calciphylaxis. Secondary hyperparathyroidism can also be caused by vitamin D deficiency, vitamin D-resistant rickets, high abnormal magnesium levels, malnutrition, and gastrointestinal malabsorption syndrome.
One of the
primary reasons for the growth of the secondary hyperparathyroidism treatment
market is an increase in the prevalence of chronic kidney disease, which is a
leading cause of secondary hyperparathyroidism. Furthermore, an increase in
disease-related research activities and product approvals contribute to market
growth. For example, Amgen's Parsabiv (etelcalcetide) was approved in Europe in
2016 for the treatment of secondary hyperparathyroidism in adult patients on
hemodialysis with chronic kidney disease. Furthermore, the increasing number of
products in the pipeline drives market expansion. However, the side effects of
secondary hyperparathyroidism treatment, such as diarrhea, vomiting, muscle
spasms, and a drop in serum calcium, may hurt the market.
Furthermore, the treatment causes a decrease in serum calcium levels, which
increases the risk of heart failure due to hypotension and decreased myocardial
performance.
The global
Secondary Hyperparathyroidism Treatment Market is expected to grow to USD
4471.4 million by 2027, up from USD 3143.6 million in 2020, at a CAGR of 5.1
percent between 2021 and 2027.
The market
for secondary hyperparathyroidism, treatment can be divided into three categories:
treatment type, distribution channel, and geography. The market can be divided
into two categories based on treatment type: surgery and drug class. Vitamin D
and derivatives, calcimimetics, and phosphate binders are subclasses of this
drug class. Calcimimetics, a drug class, are expected to grow significantly due
to their ability to bind to parathyroid cell receptors and decrease the level
of calcium in blood serum. Furthermore, the increasing product approvals of
calcimimetics contribute to the segment's rapid growth. The market can be
divided into two categories based on distribution channels: hospital pharmacies
and retail pharmacies.
Geographically,
the market for secondary hyperparathyroidism treatment is divided into North
America, Europe, Latin America, Asia Pacific, and the Middle East and Africa.
The secondary hyperparathyroidism treatment market is expected to be dominated
by North America. This can be attributed to a well-developed health-care
infrastructure, increased public awareness, and favorable economic conditions.
This can be attributed to well-developed healthcare infrastructure,
increased public awareness, and favorable reimbursement scenarios. Europe is
expected to be the market's lagging next region. However, the region's market
growth is expected to be hampered by sluggish economic growth.
Amgen Inc.,
OPKO Health, Inc., AbbVie Inc., Shire Plc, F. Hoffmann-La Roche AG, Sanofi
S.A., Kyowa Hakko Kirin Co., Ltd., Astellas Pharma Inc, KAI Pharmaceuticals,
Leo Pharma A/S and Deltanoid Pharmaceuticals are the market leaders in
secondary hyperparathyroidism treatment.

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