The global exocrine pancreatic insufficiency (EPI) therapeutics market is expected to grow to USD 2.55 billion by 2026
The rising geriatric population and the rising prevalence of Exocrine Pancreatic Insufficiency (EPI) is driving demand for therapeutics such as lipase treatment for dietic patients and chymotrypsin and trypsin level optimization, all of which are positively contributing to the growth of the Exocrine Pancreatic Insufficiency (EPI) Therapeutics And Diagnostics Market. Insufficient secretion of pancreatic enzymes like amylase, lipase, and protease, as well as sodium bicarbonate, causes EPI. Several diseases, including various types of diabetes, are linked to an increased risk of exocrine pancreatic insufficiency (EPI).
According to
a study published in Current Diabetes Reports, the prevalence of exocrine
pancreatic insufficiency (EPI) is higher in people with type 1 diabetes than in
people with type 2. As a result, an increase in the number of persons with
diabetes is expected to fuel the expansion of the exocrine pancreatic
insufficiency (EPI) treatments and diagnostics market.
The global
exocrine pancreatic insufficiency (EPI) therapeutics market was worth USD 1.49
billion in 2018 and is expected to grow to USD 2.55 billion by 2026.
Diabetes
prevalence and incidence are increasing as a result of sedentary lifestyles and
bad diets. According to a study published in Diabetes Research and Clinical In practice, the global diabetes prevalence was 463 million in 2019 and is
expected to rise to 578 million by 2030. The demand for innovative treatments
is increasing as a result of this. To meet these demands, the market's leading
companies are spending in research & development to develop and offer
innovative exocrine pancreatic insufficiency therapies, supporting market
growth. AzurRx, for example, is developing MS1819, a yeast-derived lipase that
has been designed to have higher enzymatic activity than current treatments.
For the historical period 2017–2018 and forecast period 2019–2027, the global exocrine pancreatic insufficiency (EPI) therapeutics market, the rise in prevalence of cystic fibrosis and chronic pancreatitis will exacerbate the growth of the global exocrine pancreatic insufficiency (EPI) therapeutics & diagnostics market. Furthermore, rising diabetes cases are predicted to propel the exocrine pancreatic insufficiency (EPI) therapeutics market forward.
The global
exocrine pancreatic insufficiency (EPI)therapeutics market was
valued at US$ 3.9 billion in 2018, according to the report, and is expected to
grow at a CAGR of 7.2 percent from 2019 to 2027.
Exocrine pancreatic insufficiency is most commonly caused by diabetes. Exocrine pancreatic insufficiency affects about half of cystic fibrosis newborns at birth, and another quarter develops within six months. Exocrine pancreatic insufficiency affects another 15% of people at some point throughout childhood or early adulthood.
As a result,
one of the primary drivers driving the exocrine pancreatic insufficiency
treatments and diagnostics market is an increase in the global incidence of
cystic fibrosis and chronic pancreatitis.
Pancreatic
enzyme replacement therapy (PERT) has been extensively explored for exocrine
pancreatic insufficiency associated with pancreatic disorders employing
pancrelipase products, which are usually purified from the porcine pancreas.
For numerous years, pancreatic enzyme preparations have been available as
over-the-counter medications in several areas.
However, because
of potential side effects and ineffectiveness, certain drug regulatory bodies,
such as the US Food and Drug Administration (FDA), have advised producers to
get regulatory authorization before marketing their products. Pancrelipase
products have been challenging to be approved due to the FDA's strict
requirements. As a result, market growth is being slowed.
The global exocrine pancreatic insufficiency (EPI) therapeutics market is dominated by a few key companies.
- Allergan plc,
- AbbVie, Inc.
- Nordmark Arzneimittel GmbH & Co. KG is a pharmaceutical company based in Germany.
- Digestive Care, Inc. is a company that specializes in digestive health

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